- Country: TAIWAN
- Official Title: 助理教授
- Department: 國立臺灣大學
Speech Title
Application of Polygenic Scoring in Epilepsy 多基因分數在癲癇的應用
- Introduction to Epilepsy and Genetics:
- Brief overview of epilepsy as a neurological disorder.
- The role of genetics in understanding epilepsy, including the prevalence of genetic factors.
- Understanding Polygenic Scores:
- Explanation of what polygenic scores are and how they are calculated.
- Overview of the methodology behind polygenic risk assessment.
- Current Research on Polygenic Scoring in Epilepsy:
- Review of existing studies that have utilized polygenic scoring in epilepsy research.
- Discussion of how polygenic scoring has contributed to our understanding of the genetic architecture of epilepsy.
- Implications for Diagnosis and Treatment:
- Exploration of how polygenic scores can aid in diagnosing certain types of epilepsy.
- Consideration of the potential for personalized treatment approaches based on polygenic risk profiles.
- Challenges and Limitations:
- Discuss the limitations of polygenic scoring in clinical settings, including ethical considerations.
- Address challenges such as variability in genetic expression and environmental factors.
- Future Directions:
- Suggestions for future research, including integrating polygenic scores with other genomic data.
- Potential for large-scale studies to further validate the utility of polygenic scoring in epilepsy.
- Conclusion:
- Summarize the significance of polygenic scoring in advancing our understanding of epilepsy.
- Emphasize the need for ongoing research in this area to improve patient outcomes.
These sections can help structure your research and provide a comprehensive view of the application of polygenic scoring in epilepsy.